DeCS Server - List Exact Term

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DeCS

Descriptor English:

Secretory Component

Descriptor Spanish:

Componente Secretorio

Descriptor Portuguese:

Componente Secretório

Synonyms English:

Secretory Piece

Tree Number:

Definition English:

The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.

Pharmacological Action:

History Note English:

91(76); was see under IMMUNOGLOBULIN FRAGMENTS 1976-90

Allowable Qualifiers English:

Record Number:

22287

Unique Identifier:

D012635

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